ISSN: 0973-7510

E-ISSN: 2581-690X

B. Venkata Raman , A. Sai Ramkishore2, M. Uma Maheswari2 and T.M. Radhakrishnan1
*Department of Biotechnology, Koneru Lakshmaiah College of Engineering (KLCE),
Vaddeswaram–522 502, India.
1Biotechnology Division, College of Science and Technology, Andhra University, Visakhapatnam–530 003, India.
2Department of Biotechnology, GITAM, Visakhapatnam – 530 045, India.
J Pure Appl Microbiol. 2009;3(1):187-194
© The Author(s). 2009
Received: 19/09/2008 | Accepted: 11/11/2008 | Published: 30/04/2009
Abstract

Antibacterial activity in the crude extracts of the selected parts (roots/ leaves/ fruits/ seeds/ bark) of different traditional folk medicinal plants of North Coastal Andhra Pradesh was examined. Of the 14 plants studied only 10 plants showed various levels of antibacterial activity against Gram positive (Bacillus subtilis, Staphylococcus aureus) and Gram negative (Escherichia coli, Klesbsiella pneumonia & Proteus vulgaris) bacteria with the diameters of growth inhibition zone in the range of 10–25mm. However, Abelmoschus moschatus (Fabaceae), Thespesia populnea (Malvaceae), Abutilon indicum (Malvaceae) and Amaranthus spinosis (Amaranthaceae) have not shown any antimicrobial activity in the extracts with solvents such as methanol, 95% ethyl alcohol and methanol: chloroform: water (MCW – 12:5:3) mixture. Eclipta prostrata (Compositae), which is used as folk medicine, showed antibacterial activity only in the ethyl alcohol extract of its leaves. Present studies indicate that the ten plants, which showed antibacterial activity, may be used as good sources for the isolation of the active principle(s) for therapeutic applications.

Keywords

Eastern Ghats, Antibacterial activity, fFolk medicinal plant, Gel diffusion

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