ISSN: 0973-7510
E-ISSN: 2581-690X
Abnormal liver biochemistries are a frequent feature of HIV disease. Analysis of liver-associated enzymes may help focus the diagnostic workup. The present study attempts to assess the following – 1) To study whether the liver functions are deranged in HIV positive patients by estimating the serum AST & ALT levels. 2) Whether or not aminotransferases can be used as a diagnostic & prognostic tool. The mean ± SD serum AST & ALT in control group was demonstrated to be 22.15 ± 2.67 IU/L & 17.85 ± 1.84 IU/L which was found to be increased to 95.85 ± 26.9 IU/L (p<0.001) & 85.67 ± 28.56 IU/L (p<0.001) in HIV positive patients. The increase was found to be statistically highly significant. It could be concluded that the liver function tests are deranged in HIV positive patients as compared to control. The deranged serum AST & ALT levels may identify patients requiring further investigations, thus can be used as a diagnostic & prognostic tool.
Aspartate Aminotransferase, Alanine Aminotransferase, HIV/AIDS
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