ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access

Nora Abdulaziz AL Jalaud

College of Science, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
J Pure Appl Microbiol, 2019, 13 (1): 465-473 | Article Number: 5448 | © The Author(s). 2019 

Received: 20/01/2019 Accepted: 02/03/2019 | Published: 27/03/2019

Diabetes mellitus has emerged as a pandemic affecting both the genders and all the age groups. This metabolic disorder is classically notorious to cause retinopathy, neuropathy, micro and macro vascular complications including brain damage, cardiac disorders and nephropathy and renders patients to develop various kinds of infections Ginger, Nigella sativa and Punica granatum are strong antioxidants and possess antimicrobial activity. While the Metformin is known to reduce the insulin resistance. In present study we examined the influence of Ginger, Nigella sativa, Punica granatum and Metformin on the prevention and treatment of bone damage and infections due to Diabetes Mellitus in STZ-induced diabetes in male Wistar albino rats. 40 rats were used in the study, and it was observed that all the studied substances prevented infections and bone damage at the same time, significant increase was found in the bone volume, strength, density, and length in comparison to diabetic rats.


Diabetes mellitus, Infection, Animal model, animicrobial activity.

Article Metrics

Article View: 2998

Share This Article

© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.