ISSN: 0973-7510

E-ISSN: 2581-690X

Review Article | Open Access
Telugu Seetharam Deepak1, P. Tamizharasi2, Anisha Jain3, Bhargav Shreevatsa4, D. Chandan4, Chandrashekar Srinivasa1, Sharanagouda S. Patil5, Chandan Shivamallu6 and S.M. Gopinath1
1Department of Studies in Biotechnology, Davangere University, Shivagangothri, Davangere, Karnataka, India.
2Department of Biotechnology, The Oxford College of Engineering, Bengaluru, Karnataka, India.
3Department of Biotechnology, JSS Science and Technology University, Mysuru, Karnataka, India.
4Department of Microbiology, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
5ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru, Karnataka, India.
6Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
Article Number: 11055 | © The Author(s). 2026
J Pure Appl Microbiol. 2026;20(2):916-929. https://doi.org/10.22207/JPAM.20.2.23
Received: 15 October 2025 | Accepted: 24 February 2026 | Published online: 18 May 2026
Issue online: June 2026
Abstract

The dengue virus (DENV), leading to dengue, is a mosquito-borne virus which has become a major global health concern, especially in tropical and subtropical areas. So far, no specific therapeutic drug or effective antiviral medication has been approved, despite the high rates of morbidity and mortality. The primary goal of current management regimens is symptomatic alleviation, underscoring the pressing need for innovative therapeutic approaches. Given their varied pharmacological characteristics and low side effects, medicinal plants and their bioactive phytocompounds have attracted a lot of interest as possible antiviral medicines. Several compounds derived from plants have shown inhibitory actions against various stages of the DENV life cycle, indicating that they may be effective antiviral options. The current review offers a thorough examination of medicinal plants that have been shown to have anti-dengue properties, emphasizing their modes of action and prospects for future drug development.

Keywords

Dengue, DENV, Phytocompounds, Antiviral, Medicinal Plants

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