ISSN: 0973-7510

E-ISSN: 2581-690X

Mini Review | Open Access
Mansi Upadhyay1, Anushika Swaroop1, Vijay Kumar Sinhal2, Alok Srivastava2, Sanjay Kumar Garg2, Vijay Pal Singh2 and Pankaj Kumar Arora2
1Department of Environmental Microbiology, Babasaheb Bhimrao Ambedkar University,
Lucknow, Uttar Pradesh, India.
2Department of Plant Science, Faculty of Applied Sciences, MJP Rohilkhand University, Bareilly, Uttar Pradesh, India.
Article Number: 8945 | © The Author(s). 2024
J Pure Appl Microbiol. 2024;18(1):168-176.
Received: 26 August 2023 | Accepted: 30 December 2023 | Published online: 03 March 2024
Issue online: March 2024

The human oral microbiome represents a diverse and intricate ecosystem comprising bacteria, fungi, viruses, and protozoa. It plays a vital role in numerous physiological processes, ranging from digestion to immunity. Recent research endeavors have focused on delineating the composition and functions of the oral microbiome. Changes in the oral microbiome have been associated with both oral diseases (such as dental caries, periodontitis, halitosis) and systemic conditions (including cardiovascular disease, diabetes, and cancer). Despite significant advancements, numerous questions about the role of the oral microbiome in health and disease remain unanswered. Further research is imperative to explore the intricate interactions between the oral microbiome and other microbiomes within the body. Additionally, there is a need to develop targeted interventions capable of selectively modulating the oral microbiome without disrupting other beneficial microorganisms. In summary, delving into the study of the human oral microbiome has the potential to revolutionize our comprehension of health and disease, opening avenues for innovative approaches to preventive and therapeutic medicine.


Oral Cavity, Microbiome, Periodontal Diseases, Cancer, Gingivitis

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© The Author(s) 2024. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.