ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Mohammed R. Mohaisen1,2 , Shehab A. Lafi3 and Sawasan Q.T. Al-Quhli3
1Molecular Microbiology, College of Dentistry, University of Anbar, Ramadi, Iraq.
2Institute of Infection, Veterinary, and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
3Medical Microbiology, Microbiology Department, College of Medicine, University of Anbar, Ramadi, Iraq.
Article Number: 8917 | © The Author(s). 2023
J Pure Appl Microbiol. 2023;17(4):2344-2351. https://doi.org/10.22207/JPAM.17.4.30
Received: 13 August 2023 | Accepted: 28 October 2023 | Published online: 21 November 2023
Issue online: December 2023
Abstract

Microbes show a high antimicrobial resistance due to a high rate of mutations predisposed by many factors, especially the abuse of antibiotics. Therefore, there is a great need for an alternative therapeutic agent for infectious diseases caused by microbes resistant to antibiotics. Bacteriophages are viruses parasitizing microbes, that got a big scientist’s attention due to their ability as an alternative therapy for severe bacterial infections. This study is devoted to identifying bacteriophage from river water on tested pathogenic isolates isolated from clinical cases of UTI in vitro and finding out the effect of phage on these bacterial isolates as an initial step of further in vivo phage therapeutic study on the same tested isolates. The results showed a significant bactericidal effect of the isolated bacteriophages against the pathogenic bacterial isolates.

Keywords

Phage, Bacteriophages, Phage Therapy and Resistant Bacteria

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© The Author(s) 2023. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.