Skin and soft tissue infections are brought on by invasion of microbes on the skin and underlying soft tissues (SSTIs). They appear in a series of shapes, causes the high level of severeness. Differentiating between SSTI situations that require prompt attention and surgical or medical intervention from those that don’t is difficult. SSTIs are most prevalent in emergency rooms and affect 7% to 10% of hospitalised patients. SSTIs are characterised by inflammatory components as well as other symptoms including fever, quickly growing lesions, and bullae. The creation of a severity categorization approach to specify suitable empirical treatment would improve the management of SSTIs. Based on the patient’s status knowledge of potential infections, an antibiotic medicine is chosen. Oral antibiotics are sufficient for simple mild-to-moderate infections; however, intravenous antibiotics are required for complicated severe infections.