ISSN: 0973-7510

E-ISSN: 2581-690X

Review Article | Open Access
Pooja Rani Mina
Department of Immunology, Mayo Clinic, Scottsdale, USA.
Article Number: 8448 | © The Author(s). 2023
J Pure Appl Microbiol. 2023;17(1):51-68.
Received: 23 January 2023 | Accepted: 09 February 2023 | Published online: 02 March 2023
Issue online: March 2023

Microbes proved to be the significant biotic factors that influence the health of humans. Gut microbiota remains an emerging field for understanding different aspects of microbiology, immunology, computational biology and food and nutrient supplementation studies. The human microbiome project provides a thread in the path of microbe association with humans. This review will discuss how their study was taken last year on human microbiome discovery for human health. Thus, the microbiome could be deliberated as target for treating various disorders. Despite some limitations, interventions in this field of study appear encouraging for emerging a preventive therapy by restoring microbiome functionality or as an adjuvant in specific immunotherapy. Manipulation of the gut microbiota in various disorders is assessed by examining the current most relevant evidence concerning to antibiotics, probiotics, prebiotics, polyphenols, and fecal microbiota transplantation. This review discusses the impact of gut microbiota on health and their manifestation by focusing on vital mechanisms.


Microbiota, Disease, Nutrient, Intestine, Dysbiosis

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© The Author(s) 2023. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.