ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Huda S.A. Al-Hayanni1 , Marwah Th. Alnuaimi2 , Rana AH. AL-Lami3 and Shaimaa M. Zaboon4
1Department of Biology, College of Science for Women, University of Baghdad, Iraq.
2Ministry of Science & Technology, Directorate of Environment and Water, Baghdad, Iraq.
3Department of Biology, College of Science for women, University of Baghdad, Iraq.
4Ministry of Health, Iraq.
Article Number: 8029 | © The Author(s). 2022
J Pure Appl Microbiol. 2022;16(4):2880-2890. https://doi.org/10.22207/JPAM.16.4.61
Received: 14 August 2022 | Accepted: 02 November 2022 | Published online: 01 December 2022
Issue online: December 2022
Abstract

Green synthesis of metal nanoparticles (NPs) from plant extracts has attracted significant interest in modern medicine. Therefore, this study prepared an aqueous extract of Sophora flavescens roots, which are used in folk medicine to treat several diseases, including bacterial infections. In addition, silver NPs (AgNPs) were synthesized from root extract using the green synthesis method. The NPs were diagnosed using modern methods. Additionally, the antibacterial activity of the root aqueous extract and AgNPs aqueous preparation (at concentrations of 7% and 9%, respectively) was examined against selected isolates of multidrug-resistant Pseudomonas aeruginosa and Staphylococcus aureus. The results indicated that both the plant extract and NP preparations inhibited pathogenic bacterial isolates.

Keywords

Antibacterial Activity, Green Synthesis, Multidrug-resistance Bacteria, Silver Nanoparticles, Sophora flavescens

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