ISSN: 0973-7510

E-ISSN: 2581-690X

Review Article | Open Access
Ameera M. Al-Yami1, Abeer T. Al-Mousa1, Sarah A. Al-Otaibi1 and Ashraf Y. Khalifa1,2
1Department of Biological Sciences, College of Sciences, King Faisal University, Al-Ahsa, Saudi Arabia.
2Department of Botany and Microbiology, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.
Article Number: 7933 | © The Author(s). 2022
J Pure Appl Microbiol. 2022;16(4):2270-2291.
Received: 25 June 2022 | Accepted: 13 September 2022 | Published online: 19 October 2022
Issue online: December 2022

Recently, the attention to exploring and applying probiotics has been increased. Probiotics are living microscopic organisms that have valuable impacts on health when consumed in adequate amounts. One of the most popular widespread utilized probiotics for many years until now is the Lactobacillus species which exemplifies the hugest heterogeneous group among the lactic acid bacteria (LAB) that normally occupy many environments that contain high nutrient levels such as soil, humans, waters, plants, animals and even air without causing any illness. The purpose of this work is to review and demonstrate the wide diversity of lactobacilli isolation sources and related health benefits applications of the strains discovered in order to break the familiar sources of lactobacillus spp., thereby encouraging more research into unconventional sources and opening up opportunities for clinical applications of Lactobacillus spp. As a result, the isolation sources of lactobacillus spp. in this review have been split into two groups based on the environmental condition, including fermented and non-fermented habitats described as lactobacilli probiotic sources. The unique Lactobacilli isolated from various sources are regarded as potential therapies for a variety of illnesses and physiological abnormalities, including immunomodulation, suppression of carcinogenesis, and cholesterol reduction, in addition to their capacity to guard against infections. This will be highly significant for revealing updated information about Lactobacillus spp. that has attracted considerable attention due to its potential application in clinical practices.


Lactobacillus spp., LAB, Probiotics, Health Benefits, Isolation Sources

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© The Author(s) 2022. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.