ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
B. Anu Monisha, L. Sugantha Bharathy, K. Premkumar and K. Sathiyamurthy
Department of Biomedical Science, School of Biotechnology and Genetic Engineering, Bharathidasan University, Tiruchirappalli – 620 024, Tamil Nadu, India.
Article Number: 7603 | © The Author(s). 2022
J Pure Appl Microbiol. 2022;16(3):1884-1892.
Received: 08 February 2022 | Accepted: 03 June 2022 | Published online: 12 August 2022
Issue online: September 2022

The goal of this research is on antibiotic resistance and biofilm formation of Escherichia coli on different surfaces. 37 E.coli isolates were obtained from K.A.P. Viswanatham Government Medical College, Tiruchirappalli, Tamil Nadu, India. Biochemical assays were used to re-confirm all the isolates. Ampicillin, Cefepime, Cefotaxime, Co-trimoxazole, Tetracycline and Levofloxacin showed substantial levels of resistance. Meropenem, Tigecycline, and Colistin showed the least amount of resistance. 75.6% of the E.coli strains were multidrug resistant (MDR). Biofilm formation of E.coli was higher in TSBG than in TSB in all (polystyrene, polypropylene, glass and stainless steel) surfaces. It is evident that the presence of glucose or any sugar substrate promotes biofilm development, resulting in notable antibiotic resistance. This situation is hazardous to human health.


E.coli, Antibiotic Resistance, Biofilm, Surfaces

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