ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Sweta Jangra1, Priti Agarwal2 , Manisha Khandait1, Shweta Solanki1 and Priyanka Jangra1
1Department of Microbiology, SGT University, Gurugram – 122 001, Haryana, India.
2Department of Microbiology, ESIC Medical College and Hospital, Faridabad – 121 001, Haryana, India.
Article Number: 7452 | © The Author(s). 2022
J Pure Appl Microbiol. 2022;16(3):1762-1770. https://doi.org/10.22207/JPAM.16.3.18
Received: 24 November 2021 | Accepted: 15 April 2022 | Published online: 16 July 2022
Issue online: September 2022
Abstract

Urinary tract infections are gaining much importance among community acquired infections. Poor personal hygiene may act as a contributory factor in such frequent infections in developing countries. The condition becomes serious with antimicrobial resistance among uropathogens. Specifically, surge of Extended Spectrum beta Lactamase (ESBL) producers poses much concern in the available treatment options. Present work was aimed to observe the bacteriological profile and antimicrobial susceptibility pattern of uropathogens with special reference to ESBL producing strains. This study was carried out in the microbiology department, SGT University, Gurugram, Haryana. Total 600 samples were processed as per standard bacteriological procedures i.e, microscopy, culture and biochemical reactions followed by antibiotic susceptibility testing and interpreted as per CLSI guidelines. ESBL producer strains were spotted by double disc synergy testing (DDST). Out of 600 specimens, 128( 21.3%) showed culture positivity. Females contributed more compared to males. 21-40 years age group showed highest isolation rate. E.coli was predominant organism. Highest resistance towards amikacin was shown by gram negative organisms. Gram positive organisms demonstrated high resistance towards gentamicin, cotrimoxazole, ampicillin and ciprofloxacin. 34.4% ESBL producing E.coli strains were observed. Alarming rate of antibiotic resistance as well as beta lactamase production by strains and increasing urinary tract infections should be considered as potential threat to the community. Routine investigation should be done to see the burden in order to implicate advance treatment policies in order to treat such infections.

Keywords

Urinary Tract Infection (UTI), Enterobacteriaceae, Community-Acquired Infections, Rural, ESBL

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