ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Mohammed Aljeldah1, Basim Al Shammari1, Eman S. Farrag1,Ehab M. Taha2 and Sabry Y. Mahmoud2
1Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Hafr Al Batin, Hafr Al Batin, Saudi Arabia.
2Biology Department, College of Science, Hafr Al Batin University, Hafr Al Batin, Saudi Arabia.
J Pure Appl Microbiol. 2022;16(2):1192-1199 | Article Number: 6838
https://doi.org/10.22207/JPAM.16.2.48 | © The Author(s). 2022
Received: 04/01/2021 | Accepted: 12/04/2022 | Published online: 31/05/2022
Issue online: June 2022
Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for serious threats to human health, causing various syndromes worldwide. Here, our purpose was to estimate the prevalence of nosocomial MRSA among isolates from King Khalid Hospital (KKH) and Maternity and Children Hospital (MCH) at Hafar Al-Batin Governorate, Saudi Arabia, and to determine the resistance of these isolates to common antibiotics used for treatment. One-hundred clinical specimens were collected from admitted patients during a six month period, and subjected to MRSA screening using traditional microbiological techniques. Antimicrobial susceptibility testing (AST) was also performed and confirmed by the VITEK2 automated system. Among the 37 S. aureus strains isolated from KKH, 23 (62.16%) were identified as MRSA. In MCH, 38 (60.31%) out 63 isolated strains were identified as MRSA. According to AST, few MRSA strains were resistant to teicoplanin, fosfomycin, linezolid, and mupirocin in both hospitals. Vancomycin resistance was not detected in any of the MRSA strains. Twelve MRSA strains from KKH and 17 strains from MCH were considered multidrug resistant (MDR). In conclusion, prevention is critical to reduce the high prevalence of MRSA.

Keywords

Staphylococcus aureus, MRSA, multidrug-resistant, prevalence, Saudi Arabia

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© The Author(s) 2022. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.