ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Abhishek Kumar Jain1, Harshul Patidar2, Vijay Nayak3 and Ramesh Agrawal4
1Department of Microbiology, Jaipur National University Institute for Medical Sciences and Research Center, Jaipur – 302017, Rajasthan, India.
2Department of Pathology, N.S.C. Government Medical College, Khandwa – 450001, Madhya Pradesh, India.
3Department of Anatomy, N.S.C. Government Medical College, Khandwa – 450001, Madhya Pradesh, India.
4Department of Microbiology, N.S.C. Government Medical College, Khandwa – 450001, Madhya Pradesh, India.
J Pure Appl Microbiol. 2022;16(1):700-707 | Article Number: 7506
https://doi.org/10.22207/JPAM.16.1.73 | © The Author(s). 2022
Received: 23/12/2021 | Accepted: 03/02/2022 | Published online: 25/02/2022
Issue online: March 2022
Abstract

Surgical site infection (SSI) was the predominant complication following cesarean delivery. Risk factors like increased Body Mass Index (BMI), emergency cesarean section (CS), prolonged hospital stay, previous CS, anemia, pre-existing chronic diseases, and failure to use preoperative antibiotic prophylaxis associated with SSI. Surgical site infections are responsible for cost burden, longer hospital stay increased maternal morbidity and mortality. Despite the advance, aseptic measures & control practice SSI was the most common nosocomial infection. To determine the prevalence, risk factors, bacterial profile, and antimicrobial resistance pattern of SSI in women following Cesarean section at tertiary care center western India. Women who developed SSI underwent cesarean delivery enrolled in the present study. Data were collected from patient records. Collection of swab samples, identification of microorganisms, and antimicrobial susceptibility testing was done by standard CLSI guidelines Results: Prevalence of SSI was 14.7% in this study. The risk factors significantly associated with SSI were emergency cesarean delivery, severe anemia, lack of preoperative antibiotics use, high Body Mass Index (BMI), preexisting disease, and previous history of CS, Klebsiella Pneumoniae & Staphylococcus aureus was the most predominant isolates. Imipenem was the most susceptible and Amoxycilline-Clavulanate was the most Resistance antibiotic. Prompt identification of risk factors, microbial agents, and susceptibility patterns of SSIs are beneficial for the selection of appropriate antimicrobial therapy to prevent the emergence of drug resistance, planning to make infection control & antibiotic policy, and taking appropriate steps to prevent risk factors.

Keywords

SSI, cesarean section, risk factors, microbial profile, antibiotic resistance

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