ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Suvansh Nirula1, Nusrat Nabi2 , Mohammad Daud Ali3, Arunabha Ray4, Ajaz Mustafa5, Musharraf Husain6, Pranay Kapur7, Shoma Mukherjee4 and Sanjana Aggarwal8
1General Medicine, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
2Department of Pharmacology, Hamdard Institute of Medical Sciences and Research (HIMSR), Jamia Hamdard University, New Delhi 110062, India.
3Department of Pharmacy, Mohammed Al-Mana College for Medical Sciences, Al Safa, Dammam, Saudi Arabia.
4Department of Pharmacology, Hamdard Institute of Medical Sciences and Research, New Delhi – 110062, India.
5Medical Superintendent, HIMSR-HAH Centenary Hospital, New Delhi – 110062, India.
6Department of Surgery, HAHC Hospital, Hamdard Institute of Medical Sciences and Research, New Delhi – 110062, India.
7Department of Medicine, HAHC Hospital, Hamdard Institute of Medical Sciences and Research, New Delhi – 110062, India.
8Hamdard Institute of Medical Sciences and Research, New Delhi – 110 019, India.
J Pure Appl Microbiol. 2022;16(1):685-695 | Article Number: 7502
https://doi.org/10.22207/JPAM.16.1.70 | © The Author(s). 2022
Received: 22/12/2021 | Accepted: 28/01/2022 | Published online: 25/02/2022
Issue online: March 2022
Abstract

This study assessed antimicrobial prescription at our institute to promote rational antimicrobial use and implement customized antimicrobial stewardship programs. This study is a cross sectional point-prevalence survey on antimicrobial utilisation conducted at HAH Centenary hospital, New Delhi in April, 2019, over a period of 3 days. All in-patients were included in the analysis. However, neonates, emergency room patients and palliative care patients, orders for anti-viral, anti-fungal, anti-tubercular and anti-parasitic medications were excluded. SPSS version 13.0 was planned to be used for analysis of the statistical data. The number of patients admitted at the point of time of our survey was 217, out of which 101 (46.54%) patients were receiving antimicrobial agents (AMA) with 160 (73.73%) AMAs prescribed. 50 patients (49.5%) were prescribed AMAs for infections, whereas, 49 patients (48.51%) were prescribed AMAs prophylactically and 2 (1.98%) patients received AMAs for reasons not defined. The intensive care units exhibited 93.33% patients receiving antimicrobials. The most common indication was intra-abdominal infections (32.40%). The most commonly used antibiotics were beta-lactam antibiotics (60.62%). The study suggests a high rate of antimicrobial use and highlights areas for intervention for rational antimicrobial use. We propose to sensitise the government on initiating a national antimicrobial stewardship program such as the Global Point Prevalence Survey and facilitate evidence-based antimicrobial practice.

Keywords

Antimicrobial utilization, Antimicrobial stewardship, Antimicrobial resistance, Point prevalence survey

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© The Author(s) 2022. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.