ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Noor Zarina Abd Wahab1 , Nur Saidatul Aqilah Ja’afar2 and Samhani Binti Ismail3
1School of Biomedicine, Faculty of Health Sciences, Universiti Sultan Zainal Abidin, Kuala Nerus, Terengganu, Malaysia.
2School of Health Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian, Kelantan, Malaysia.
3Faculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, Terengganu, Malaysia.
J Pure Appl Microbiol. 2022;16(1):549-556 | Article Number: 7391 | © The Author(s). 2022
Received: 25/10/2021 | Accepted: 01/01/2022 | Published online: 25/02/2022
Issue online: March 2022

Melaleuca cajuputi Powell is a tree species belonging to the family Myrtaceae and is widely used in traditional medicine. This study was conducted to investigate the antibacterial activities of essential oils of M. cajuputi Powell. Antibacterial activity was tested against Gram positive and Gram negative bacteria using the agar disc diffusion method. The essential oils of M. cajuputi were found to exert antibacterial activity against all of the tested bacteria, including Staphylococcus aureus, Streptococcus pyogenes, methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, and Escherichia coli. The zones of inhibition for S. aureus, S. pyogenes, MRSA, E. coli, and K. pneumoniae were 12.7 mm, 10.7 mm, 10.0 mm, 8.7 mm and 9.3 mm respectively, against 0.714% (w/w) of the essential oils. These results highlighted that Gram negative bacteria are less susceptible to the essential oils of M. cajuputi. A large zone of inhibition might be a sign of a leaching antimicrobial agent. These findings suggest that M. cajuputi is a potential natural antibacterial agent.


Melaleuca cajuputi Powell, essential oils, antibacterial, minimum inhibitory concentration

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© The Author(s) 2022. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.