ISSN: 0973-7510

E-ISSN: 2581-690X

Review Article | Open Access
Fataneh Hashempour-Baltork1, Mahdieh Sheikh1, Sevda Eskandarzadeh2, Fatih Tarlak3, Abhishek Dutt Tripathi4, Kianoush Khosravi-Darani1 and Amankeldy Sadanov5
1Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
3Department of Nutrition and Dietetics, Faculty of Health Science, Istanbul Gedik University, Istanbul, Turkey.
4Department of Dairy Science and Food Technology, Institute of Agricultural Sciences,
Banaras Hindu University, Varanasi – 22105, Uttar Pradesh, India.
5Department of Science, Ministry of education and science, Institute of Microbiology and Virology, Almaty, Kazakhstan.
J Pure Appl Microbiol. 2021;15(3):1042-1058 | Article Number: 7147 | © The Author(s). 2021
Received: 09/06/2021 | Accepted: 30/06/2021 | Published: 06/07/2021

Probiotic bacteria play a critical and functional role in clinical and nutritional applications. In the present study, the ability of various probiotics and their metabolites in the prevention and treatment of different diseases, infections and disorders was reviewed. The issues that were noticed are included: Fibrocystic, diabetes, acne, colon cancer, cardiovascular, urinary tract infections, atopic eczema syndrome, food allergies and obesity. Enhancement in using drug treatment has led to the appearance of drug-resistance concern, thus probiotics can be a suitable choice. This review focuses on the effect of probiotic bacteria and their metabolites on immune-boosting, prevention and treatment of these diseases. For this purpose, after a short glance at each disease, infection and disorder, the mechanism of probiotic action and recent studies about that disease are reviewed. It could be recommended that probiotics consumption, perhaps from birth to all stages of life, would be effective in the life-long, development of health effects and disease treatments.


Probiotic, disease, fibrocystic, acne, urinary tract infections, atopic eczema syndrome

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© The Author(s) 2021. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.