ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
R. Bindu Madhavi1 and A.R. Hanumanthappa2
1Department of Microbiology, Sri Devaraj Urs Medical College, SDUAHER, Kolar-563103, India.
2Department of Microbiology, JJM Medical College, Davangere-577004, India.
J Pure Appl Microbiol. 2021;15(3):1173-1179 | Article Number: 6709 | © The Author(s). 2021
Received: 17/10/2020 | Accepted: 10/06/2021 | Published: 23/06/2021

Hospital-acquired infections (HAIs) are continuing to be a major risk in health care settings. World Health Organization (WHO) describes surgical site infections (SSIs) as one among the major health issue, causing enormous burden to both patients as well as doctors.  Multidrug-resistant pathogens that cause SSIs continue to be an ongoing and increasing challenge to health care settings. The objective of the present study was to know the prevalence of extended-spectrum beta-lactamase (ESBL) producing gram-negative bacilli causing SSIs at a tertiary healthcare facility. The present cross-sectional observational study was done for a period of one year. Pus samples from clinically suspected cases of SSIs were collected and subjected to bacterial culture and sensitivity testing. From the total of 140 samples collected, a total of 138 bacterial isolates were isolated. Out of 138 isolates, 85 isolates (61.6%) were identified as gram-negative bacilli of which 33 isolates (38.8%) were identified to be ESBL phenotypes. Majority of the ESBL phenotypes were Escherichia coli (25.9%) followed by Klebsiella pneumoniae (7%), Acinetobacter species (2.4%), Pseudomonas aeruginosa (2.4%) and Proteus species (1.2%).  Regular surveillance of antibiotic sensitivity pattern and screening for beta-lactamase production should be done which helps to know the trends of pathogenic bacteria causing SSI and guides in planning antibiotic therapy.


ESBL, Surgical site infection (SSI), Hospital-acquired infections (HAI), antimicrobial resistance

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© The Author(s) 2021. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.