ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Javid Iqbal Rather1, Zahoor Mohi ud din2, Farkhanda N. Syed2,
Mir Haris2, Mudasar Nabi3, Ambreena Farooq3, Bilal Ahmad Tantry4 , Abdul Hafeez Muhammed4 and Shaik Rahiman5
1Department of Physiology, GMC Srinagar, Kashmir, Jammu and Kashmir, India.
2Department of Microbiology, GMC Srinagar, Kashmir, Jammu and Kashmir, India.
3Department of Clinical Biochemistry, University of Kashmir, Srinagar, Kashmir, Jammu and Kashmir, India.
4Department of Microbiology, Jouf University, College of Medicine, Saudi Arabia.
5Department of Biochemistry, Jouf University, College of Medicine, Saudi Arabia.
J Pure Appl Microbiol. 2021;15(1):421-427 | Article Number: 6841
https://doi.org/10.22207/JPAM.15.1.39 | © The Author(s). 2021
Received: 06/01/2021 | Accepted: 16/02/2021 | Published: 27/02/2021
Abstract

Extended Spectrum beta lactamase producing pathogens are reported in many clinical samples and pose an emerging threat health. To find the prevalence of ESBL producing Enterobactriacea pathogens isolated from inpatients (Medical and Surgical Wards; Hospital stay > 72 h) admitted to Prince, Mutib, Hospital Sakaka, Jouf. A total of 1043 Enterobactriacea were isolated during April 2015 to October 2016 study period. Vitek -2 compact (biomeriux Leon, France) was used for identification and antimicrobial sensitivity (AST) test. A Total of 115/1043 (11.02%) ESBL producing pathogens were isolated from urine 15.07% (n=242), sputum 13.6 % (n=220), wound 10.8% (n=287) and blood 5.4 % (n=294). Klebsiella pneumonia is most dominant followed by E coli and Proteus miribilis. Cephamycins and carbapenems were found most effective (100% sensitivity) against the pathogens isolated. The aminoglycosides, beta lactams and Fluroquinolnes class of antibiotics, microorganisms have gained the resistance of 20%, 22.7%, 40-70% respectively. The infection control measures should be taken seriously and making of effective use of antibiotics is need of hour.

Keywords

ESBL, Gram negative bacteria, Antimicrobial sensitivity test, Antibiotics

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