ISSN: 0973-7510

E-ISSN: 2581-690X

Review Article | Open Access
Rinki Kumari1 , Anita Venaik2, Md Al Hasibuzzaman3, Simon Agongo Azure4, Rudra P. Ojha5 and Ajay Kumar Sahi6
1Department of Microbiology, Hind Institute of Medical Sciences, Mau Ataria, Sitapur Rd, Uttar Pradesh – 261303, India.
2Department of General Management, Amity Business school, Amity University,
Noida – 2013132, Uttar Pradesh, India.
3Ningbo university medical school, Ningbo City, Zhejiang Province – 315211, PR China.
4Department of Community Health, College of Health, Yamfo, Ghana.
5Department of Zoology, Nehru Gram Bharati (Deemed University), Prayagraj, Uttar Pradesh, India.
6School of Biomedical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi – 221005, Uttar Pradesh, India.
J Pure Appl Microbiol. 2021;15(1):1-19 | Article Number: 6860 | © The Author(s). 2021
Received: 17/01/2020 | Accepted: 03/02/2021 | Published: 23/02/2021

Coronavirus disease (COVID) is highly contagious, and negligence of it causes high morbidity and mortality globally. The highly infectious viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was abbreviated as COVID-19 (Coronavirus disease 2019) by World Health Organization first time on February 11, 2020, and later on, WHO declared COVID-19 as a global pandemic on 11/3/2020. Epidemiological studies demonstrated that the SARS CoV-2 infects the overall population, irrespective of age, gender, or ethnic variation, but it was observed in clinical studies that older and compromised immunity population is much more prone to COVID-19. SARS-CoV-2 majorly spread through aeration route in droplet form on sneezing and coughing, or by contact when touching eyes, nose or mouth with the infected hands or any other organs, resulting from mild to severe range of SARS-CoV-2 infection. This literature-based review was done by searching the relevant SCI and SCOPUS papers on the pandemic, SARS-CoV-2 and COVID-19, herbal formulation, and Ayurveda from the databases, Academia, Google Scholar, PubMed, and ResearchGate. The present review attempts to recognize the therapeutic strategies to combat COVID-19 because of the current human risk. Indian system of medicine, including herbals, has immense potential in treating and managing various viral infections and provides evidence to utilize Ayurvedic medication to improve immunity. Cumulative research findings suggest that Ayurvedic formulations and herbal immunomodulators (Tino sporacordifolia, Withania somnifera, Crocus sativus, Zafran, Allium sativum, Zingiber officinale, Albizia lebbek, Terminalia chebula, Piper longum, Mangifera indica, Ocimum sanctum, Centella asiatica ) are promising in the treatment of outrageous viral infections without exerting adverse effects. Considering the ancient wisdom of knowledge, the herbal formulations would compel healthcare policymakers to endorse Ayurveda formulations to control the COVID-19 pandemic significantly.


COVID-19, Ayurveda, Immunomodulators, Herbals, Viral infections, anti-viral

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© The Author(s) 2021. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.