ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Shanmuga Priya C1, R. Prabha1 and M. Rajesh2
1Department of Microbiology, Mahatma Gandhi Medical College and Research Institute,Sri Balaji Vidyapeeth, (Deemed to be university), Pillaiyarkuppam, Puducherry – 607 402, India.
2Department of Dermatology, Venerology and Leprosy,Mahatma Gandhi Medical College and Research Institute,Sri Balaji Vidyapeeth, (Deemed to be university), Pillaiyarkuppam, Puducherry – 607 402, India.
J Pure Appl Microbiol. 2020;14(4):2661-2667 | Article Number: 6508
https://doi.org/10.22207/JPAM.14.4.43 | © The Author(s). 2020
Received: 29/06/2020 | Accepted: 21/10/2020 | Published: 25/11/2020
Abstract

The virulence factors of dermatophytes play a vital role in the etio-pathogenesis and emergence of drug resistance. Regular surveillance is essential for constant monitoring of association of virulence factors in the emergence of drug resistant isolates and to guide proper therapeutic strategies to combat infections due to drug resistant isolates of dermatophytes. The aim of this study is to isolate and identify various enzymatic and non-enzymatic virulence factors of dermatophytes isolated from clinically suspected cases of dermatophytosis attending the dermatology outpatient clinic. From 30 clinical samples received from department of Dermatology to the department of Microbiology during the study period July to December 2019, KOH mount and fungal culture was done and only the isolates which grew dermatophytes were used for detecting virulence factors using standard methods. Among 30 affected patients, 13 were male (43.3%) and 17 were female (56.7%) with age range of 13 to 60 years. Skin sample yielded positive growth in 96.6% of the cases. Out of 30 samples, 6 samples were positive for Trichophyton mentagrophytes. Tinea corporis was the common manifestation which yielded positive growth. Female predominance was seen. Male predominance was seen in younger age group while females were more commonly affected in older age group. Adolescents were commonly affected age group (40%). Then people between age 41-50 (middle age group) were mostly affected. The six Trichophyton mentagrophytes were found to have enzymatic and non- enzymatic virulence factors. All the virulence factors included in the study were present in Trichophyton mentagrophytes.

Keywords

Anti-fungal susceptibility, Trichophyton mentagrophytes, Tinea corporis

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