ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Praful S. Patil1, Dhruba Hari Chandi1, Smita Damke1, Shital Mahajan1,
R. Ashok2 and Silpi Basak1
1Department of Microbiolgy, JNMC, Sawangi( Meghe) Wardha – 442 004, Maharashtra, India.
2Govt. Medical College, Dungarpur – 314 001, Rajasthan, India.
J Pure Appl Microbiol. 2020;14(3):1935-1939 | Article Number: 6283
https://doi.org/10.22207/JPAM.14.3.32 | © The Author(s). 2020
Received: 02/05/2020 | Accepted: 24/07/2020 | Published: 29/09/2020
Abstract

Dengue disease is caused by dengue virus which is a vector born viral infection. The prevalence of dengue has increased dramatically from past few decades. The clinical symptoms vary from asymptomatic to severe hemorrhagic fever leads to high morbidity and mortality.  Method- This retrospective study was carried out during January 2019 to December 2019. The laboratory test was done by using J Mitra & Co on Day 1 of their visit to the hospital which shows NS1, IgM and IgG reactivity towards dengue fever.  The clinical profile information data was collected from patient records. Out of 640 samples 62.18% (398) was positive. The percentage of positive males and females were 60.78%, 64.23% respectively. The highest prevalence of dengue infection was observed more in age group between 31-40 years (81.69%) and least prevalence in age group 71-80 years (36.36%).  Most of the patients were positive for NS1Ag121 (30.4%) followed by IgM positive 87 (21.9%) & 59 (14.8%) positive for both IgM and NS1 Ag The highest number of infections was seen during October (75.8%) post monsoon season. All patients had a fever, followed by head ache (82%) and body pains (66.4%), 64.84% stayed in the hospital less than 5 days. In tropical and sub-tropical regions dengue is still a leading public health problem especially during rainy and post monsoon seasons. Both NS1 Ag and IgM detection in early acute phase has potential diagnostic value. So, to reduce mortality there need to initiate community-based cohort studies to predict the pace of dengue spread based on clinical presentation and laboratory findings during epidemics in India. Aedesaegypti is a common vector for transmission of DENV, CHIKV and ZIKV, so there is a need to screen for these infections in endemic areas.

Keywords

Dengue, (NS1)Nonstructural Protein I, Immunoglobulin G( IgG), Immunoglobulin M (IgM)

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