ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Shriram Dorairaj Gunasekaran1, Godfred Antony Menezes2 , Rezmitha Zulfihar Nazeem1, Mohammad Obada Sultan1, Tejaswini Archarya1, Shaista Khadim1, Resshme Kannan Sudha1, Harshita Janardhan1, Mrinali Sanjay Bhatia1, Farzeen Fathima1, Khulood AlKhateri3, Michael Magaogao1, Sara Babiker Ali3, Hanadi Elias Hassan3, Essam El-Din Mahran Aly3 and Azan Saleh Al Saadi1,3
1RAK College of Medical Sciences (RAKCOMS), RAK Medical & Health Sciences University (RAKMHSU), Ras Al Khaimah, UAE.
2Associate Professor & Clinical Microbiologist, RAK College of Medical Sciences (RAKCOMS),
RAK Medical & Health Sciences University (RAKMHSU), Ras Al Khaimah, UAE.
3Saqr Hospital, Ras Al Khaimah, UAE.
J Pure Appl Microbiol. 2020;14(3):1737-1748 | Article Number: 6059 | © The Author(s). 2020
Received: 27/01/2020 | Accepted: 16/07/2020 | Published: 01/09/2020

Blood Stream Infection (BSI) and Urinary Tract Infection (UTI) being leading causes of morbidity and mortality represent a common complication among critically ill patients. During the last decade, clinicians have observed a rising occurrence of BSIs due to bacterial resistance. Likewise, catheter-associated UTI is a main cause of morbidity and mortality affecting all age groups. Coliforms happen to be the prominent pathogens among our ICU admitted patients. It was alarming to notice 42.9% resistance to tigecycline among K. pneumoniae isolated from blood. K. pneumoniae isolates cultured from urine of ICU patients uniformly displayed 75% resistance to ciprofloxacin, ceftriaxone, cefoxitin and cefepime. Interestingly, it is of respite to observe 85.7% K. pneumoniae isolated from blood and 75% K. pneumoniae isolated from urine being susceptible to a conventional antibiotic, gentamicin. Escherichia coli isolated from urine were 100% susceptible to carbapenems and 91.75% were susceptible to tigecycline. Overall, 90% of Pseudomonas aeruginosa were susceptible to nitrofurantoin. The rapid spread of these MDR pathogens demands for national and regional guidelines. Policies to treat ICU related infections in UAE should be designed based on local microbiological data and resistance profiles of pathogens.


Antimicrobial Resistance, pathogens, Blood Stream Infections, Urinary Tract Infections, Intensive Care Unit Patients

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© The Author(s) 2020. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.