ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Atipat Yasiri1 and Supawadee Seubsasana2
1Chulabhorn International College of Medicine, Thammasat University, Pathum Thani 12120, Thailand.
2Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.
J Pure Appl Microbiol. 2020;14(3):1715-1722| Article Number: 6506 | © The Author(s). 2020
Received: 30/06/2020 | Accepted: 04/09/2020 | Published: 23/09/2020

The interesting application of bile salt hydrolase enzyme is reduction of cholesterol in serum and amelioration lipid profile. While uricase enzyme can be applied to convert insoluble uric acid to be soluble form and excrete from the body. Probiotics are living organisms with generally know that they can provide beneficial effects to their host. Several reports show that probiotic bacteria with bile salt hydrolase and uricase can improve hypercholesterolemia and hyperuricemia patient. The novel isolate of Lactobacillus from Pak Sian Dong in this study is identified as L. brevis SF121 and probably use as probiotic bacteria in the future. However, this isolate still need further experiments to investigate and improve properties of probiotics. Moreover, this finding suggests that Pak Sian Dong or fermented spider plant can be designated as a good source for probiotic screening and also defines as health-promoting diet.


Lactobacillus, bile salt hydrolase, uricase, spider plant

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© The Author(s) 2020. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.