Methak Jasim AL-Jboory
University Musstansiryah, College of Sciences/Iraq.
ABSTRACT
The present study was carried out to detect the association of microRNA-146a haplotypes polymorphisms with Systemic lupus erythematous (SLE) in Iraqi patients, PCR-SSCP technique used in present study, blood was used to DNA extraction, the results show that there was strong association between microRNA-146a and SLE in one haplotype from two .The present study concluded that there was association between microRNA-146a polymorphisms with SLE, our finding need more investigation to use this polymorphism as early indication of SLE incidence .
Keywords: Lupus ,MicroRNA, miR-146a, PCR-SSCP technique, Haplotypes, Polymorphisms.