Gold Nanoparticles and Laser As Antimicrobial Agents Against Some Types of Bacteria

Maysa S. M. Al-Shukri

DOI: http://dx.doi.org/10.22207/JPAM.11.4.17

(Received: 10 September 2017; accepted: 05 November 2017)

Abstract:

The goal of this studywas to assess the efficacy of gold nanoparticles (AuNPs) and AuNPs– Low level laser combined therapy as antibacterial agents against different types of bacterial isolates in vitro.Five concentrations of AuNPs (25,50,75, 100 and 200 μg/mL) were employed for assessingbacterial growth rate and the bacterial MIC. It was found that there wasslight reducein bacterial growth after treatment with gold nanopracticle.The influence of gold nanoparticles on Staphylococcus aureus biofilms was also studied.It was found that biofilm growth was decreased at different concentrations of AuNPs compared to absence of nanoparticles.Results of the cytotoxic act of AuNPs and low level laser effectin combination againstEscherichia coli and S.aureus referred that the low level laser light improved the antibacterialactionof AuNPs when it used in combination with low level laser

Keywords:

Gold nanoparticles, Laser, Antibacterial agent,Cytotoxicity, MIC.