Nisarat Siriwatanametanon1*, Wanwisa Dodgson2
and Jolyon L.A. Dodgson2
1Department of Pharmaceutical Botany, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
2Microbiology and Applied Microbiology Research Unit, Faculty of Science, Mahasarakham University, Mahasarakham, Thailand.
Thirteen medicinal plants used in Thai traditional medicine for the treatment of inflammatory diseases were screened for in vitro antibacterial and antifungal activities. The agar disc diffusion method was employedagainstfivestrains of bacteria (Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosaandSalmonellatyphi) and fourstrains of fungi(Candida albicans, Candida tropicalis,Candida glabrata and Candida guilliermondii). The13plants wereextracted with methanol and the antimicrobial results were evaluated as the diameter of the inhibition zone of microbial growth. The results showed that the extract with the greatest activity against the gram-positive bacteria was Garciniamangostana (peri-carb). The extract with the greatest activity against the gram-negative bacteria was Psidiumguajava (leaves). The extracts with the greatest activity against Candida was Psidiumguajava(leaves) and Allium sativum (bulbs). The results support the ethnopharmacological uses of the tested plants, especiallyG.mangostana, P.guajavaand A.sativum.
Keywords: Antibacterial, Antifungal, Garciniamangostana,Psidiumguajava, Allium sativum.