Necropsy was conducted for thirty-five dead bovines during the six months duration from February to July 2016 at post-mortem facility, IVRI. Detailed post-mortem examination was done by impression smear, gross and histopathological lesions examination. Out of thirty-five cases, eight showed the septicemic changes like petechial haemorrhages on serosal surface. The necropsy examination of these cases revealed the consolidation of lungs and haemorrhages on the epicardium, spleen, and small intestine. Gross lesions were correlated with the microscopic lesions. Microscopic examination showed diffuse congestion and haemorrhages along with the neutrophilic infiltration in different organs including lung, heart, and intestine. Impression smear from heart (8 samples) showed bipolar organism under microscope by Leishman’s stain. Based on the gross and microscopic examination along with further confirmation by bipolar staining in heart impression smear indicates septicaemia by Pasteurella multocida organism which leads to death of animals.