To compare the prevalence of Methicillin Sensitive Staphylococcus aureus (MSSA) and Methicillin Resistant Staphylococcus aureus (MRSA) at a rural and urban setup and their susceptibility patterns to various antimicrobial agents. A Total of 8611 pus samples from both rural based tertiary care centre and urban based tertiary care centre were analysed. Samples with confirmed Staphylococcus aureus were subsequently tested for methicillin sensitivity and resistance using cefoxitin disc (30 µg) and antibiotic susceptibility pattern was determined. The data was analysed statistically. The prevalence or MSSA and MRSA in rural setup were 46% and 54% respectively. The prevalence or MSSA and MRSA in urban setup were 52.9% and 47.1% respectively. Isolation of MRSA is more in adults of more than 50 years of age (58.08%) in rural setup. The MSSA were sensitive to cloxacillin, amikacin, tetracycline, cephelexin, linezolid and vancomycin compared to MRSA in both the setups. The present study showed MRSA were more prevalent than MSSA in rural setup and MSSA were more than MRSA in urban set up. There was high resistance to both the groups, indicating the need for developing appropriate antibiotic policy and limiting the use of powerful antibiotics in the rural setup.
Methicillin Sensitive Staphylococcus aureus (MSSA), Methicillin Resistant Staphylococcus aureus (MRSA), Rural, Urban, Antimicrobial susceptibility
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