Acinetobacter baumannii is a Gram-negative bacterium frequently found in intensive care patients, patients with burns, and those with skin infections and pneumonia. These bacteria can cause necrotizing pneumonia and trigger inflammation, making the lung tissue more susceptible to pneumothorax. Here, we present the case of a male patient who experienced two episodes of secondary spontaneous pneumothorax due to A. baumannii infection. This case highlights the role of A. baumannii infection in patients with secondary spontaneous pneumothorax and the importance of appropriate management to prevent further complications.