Bacterial Blight of clusterbean(BLB), which is brought on by Xanthomonas axonopodis pv. cyamopsis, is a significant disease that causes severe infestation, resulting in losses of 58-68% of seed production. In order to determine the best BLB management measures, two-year field experiments and laboratory investigations were carried out in Bikaner, Rajasthan. The experiment was carried out on the BLB-susceptible cv. RGC-986. Garlic clove extract showed the most efficacy (12.80 mm) when evaluated in lab trials against Xanthomonas axonopodis pv. cyamopsis, whereas P. fluorescens bioagents revealed the highest efficacy (18.10 mm). Streptocycline, an antibiotic with strong antimicrobial activity that inhibited the pathogen and exhibited maximum growth of inhibition, 21.34 mm at 200 ppm, while Copper Oxy Chloride, a fungicide, had a maximum growth inhibiting activity as 19.60 mm at a dose of 1000 ppm. The field experiment’s findings revealed that all treatments significantly reduced disease severity and net return while also increasing seed yield when compared to the control treatment. The maximum per cent disease reduction 92.11% and 88.77% was recorded after 45 and 60 days, respectively with T₇ (T₁₊One spray of Streptocycline (150 ppm + Copper oxy chloride 0.2%). The treatment that was least effective was seed soaking with validamycin (200 ppm), followed by streptocycline at 150 ppm and then by COC at 0.2%.