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    <front>
        <journal-meta>
            <journal-id journal-id-type="issn">0973-7510</journal-id>
            <journal-title-group>
                <journal-title>Journal of Pure and Applied Microbiology</journal-title>
            </journal-title-group>
            <issn pub-type="epub">2581-690X</issn>
            <publisher>
                <publisher-name>DR. M.N. Khan</publisher-name>
            </publisher>
        </journal-meta>
        <article-meta>
            <article-id pub-id-type="doi">10.22207/JPAM.20.2.23</article-id>
            <title-group>
                <article-title>Phytochemicals Targeting the Dengue Virus Life Cycle: Molecular Mechanisms and Antiviral Evidence</article-title>
            </title-group>
            <contrib-group>

								<contrib contrib-type="author">
                    <name>
                       <surname>Deepak</surname>
                        <given-names>Telugu Seetharam</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-1"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Tamizharasi</surname>
                        <given-names>P.</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-2"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Jain</surname>
                        <given-names>Anisha</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-3"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Shreevatsa</surname>
                        <given-names>Bhargav</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-4"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Chandan</surname>
                        <given-names>D.</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-4"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Srinivasa</surname>
                        <given-names>Chandrashekar</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-1"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Patil</surname>
                        <given-names>Sharanagouda S.</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-5"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Shivamallu</surname>
                        <given-names>Chandan</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-6"/>
                </contrib>

				<contrib contrib-type="author">
                    <name>
                       <surname>Gopinath</surname>
                        <given-names>S.M.</given-names>
                    </name>
                    <xref ref-type="aff" rid="aff-1"/>
                </contrib>
				
			</contrib-group>


          <aff id="aff-1">Department of Studies in Biotechnology, Davangere University, Shivagangothri, Davangere, Karnataka, India.</aff>
          <aff id="aff-2">Department of Biotechnology, The Oxford College of Engineering, Bengaluru, Karnataka, India.</aff>
          <aff id="aff-3">Department of Biotechnology, JSS Science and Technology University, Mysuru, Karnataka, India.</aff>
          <aff id="aff-4">Department of Microbiology, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.</aff>
          <aff id="aff-5">ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru, Karnataka, India.</aff>
          <aff id="aff-6">Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.</aff>



            <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-05-18">
                <day>18</day>
				<month>05</month>
                <year>2026</year>
            </pub-date>
            <volume></volume>
            <issue></issue>
            <fpage></fpage>
            <lpage></lpage>
            <permissions>
                <copyright-statement>Copyright &#x00A9; 2026 The Author(s)</copyright-statement>
                <copyright-year>2026</copyright-year>
                <license license-type="open-access"
                    xlink:href="https://creativecommons.org/licenses/by/4.0/">
                    <license-p>This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.<uri
					xlink:href="https://creativecommons.org/licenses/by/4.0/"
                            >https://creativecommons.org/licenses/by/4.0/</uri></license-p>
                </license>
            </permissions>
            <self-uri xlink:href="https://microbiologyjournal.org/phytochemicals-targeting-the-dengue-virus-life-cycle-molecular-mechanisms-and-antiviral-evidence/"/>
            <abstract>
                <p>The dengue virus (DENV), leading to dengue, is a mosquito-borne virus which has become a major global health concern, especially in tropical and subtropical areas. So far, no specific therapeutic drug or effective antiviral medication has been approved, despite the high rates of morbidity and mortality. The primary goal of current management regimens is symptomatic alleviation, underscoring the pressing need for innovative therapeutic approaches. Given their varied pharmacological characteristics and low side effects, medicinal plants and their bioactive phytocompounds have attracted a lot of interest as possible antiviral medicines. Several compounds derived from plants have shown inhibitory actions against various stages of the DENV life cycle, indicating that they may be effective antiviral options. The current review offers a thorough examination of medicinal plants that have been shown to have anti-dengue properties, emphasizing their modes of action and prospects for future drug development.</p>
		</abstract>
		<kwd-group>
        <title>Keywords</title>
        <kwd>Dengue</kwd>
        <kwd>DENV</kwd>
        <kwd>Phytocompounds</kwd>
        <kwd>Antiviral</kwd>
        <kwd>Medicinal Plants</kwd>
		</kwd-group>
</article-meta>
</front>
</article>
