The study mediates silver nanoparticles (AgNPs) synthesis from Euphorbia geniculata and is evaluated for its multifunctional applications in healthcare, agriculture, and environmental sustainability. The AgNPs showed bactericidal activity against an array of human pathogens, including Escherichia coli, Salmonella typhi, and Bacillus cereus, with a 1.3 cm zone of inhibition and a 1.1 cm zone of inhibition against Staphylococcus aureus. The antioxidant potential of AgNPs were authenticated with the DPPH assay, which demonstrated scavenging activity of 43.22% at 75 mg. Plant growth promotion of AgNPs was evaluated, which showed an increase in the root and shoot length. The AgNPs also displayed dye degradation efficacy with a time interval of 24 hours. The AgNPs were biophysically characterized via spectroscopic analysis, which depicted a maximum peak at 418 nm. FTIR analysis revealed the functional groups at different frequencies, with major groups identified as hydroxyl and carboxyl groups. The size distribution pattern of AgNPs was studied with DLS analysis, showing the size of the particles as 201 nm. The morphological characterisation using TEM showed polydispersity from 10 nm to 100 nm. Additionally, XRD results proved the crystalline structure of synthesised AgNPs, showing the 2θ peaks at 38°, 44°, 64°, and 77°. The Phyto metabolomic studies of Euphorbia geniculata showed 40 different active phytocomponents in the methanolic extract. Some of the major metabolites include derivatives of 1-butanol, oleic acid, and n-hexadecanoic acid through GC-MS analysis. Overall, the study demonstrates the multifunctional properties of nanoparticles with profound activities.