Knowledge and Perception on Prevention of Hospital Acquired Infections (HAI) among Health Care Professionals in Tertiary Care Teaching Hospital

© The Author(s) 2020. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Jeyasheelan et al. | J Pure Appl Microbiol | 14(2):1527-1536 | June 2020 Article 6297 | https://doi.org/10.22207/JPAM.14.2.51


InTRODUCTIOn
Hospitals around the world, health workers are playing a major role in treating patients with health-related problems and infections. Hospital-acquired infections (HAIs) are the major challenge across the globe as the HAIs markedly influence the quality of health care delivery, mainly by adding burden to the underdeveloped and developing countries 1 . The main mode of transmission of HAIs is from patient to patient through health care professionals who did not follow the standard precautions 2 . HAI is not present at the time of hospitalization of the patient but has acquired by the patient within the time frames of 48-72 hours after hospitalization, 3 days after leaving the hospital, 30 days after surgery, or 1 year after the implant 2 .
World Health Organization (WHO) has defined the Hospital-acquired infection (HAI) (or) Nosocomial infection (or) Health care-associated infection, as an infection acquired in a hospital or other health care facility 3 . HAI will lead to create a greater effect on the healthcare economy by attenuating high risk area stay, lengthening the hospital stay, and increasing the chance for the need of invasive procedures. There are many HAIs, among them the most common are urinary tract infections (UTI), primary bloodstream infections (BSI), surgical site infections (SSI), and ventilatorassociated pneumonia (VAP) 4 .
Health-care workers and asymptomatic patients who are carrying pathogenic superbugs act as the platform for the spread of such infections to other patients who are seeking medical care. More than seven million HAI cases occur every year 5 . Among 20 people admitted to the hospital, at least one person will be affected by HAI, which leads to more than 90,000 death cases yearly and imposes a thirty million price burden to the community 5 . A study conducted by the WHO in more than 50 hospitals in 14 countries revealed that more than 8.7% of the patients hospitalized have been infected with hospital-acquired infections 6 .
Retention of knowledge, attitudes and practices can be achieved through continuous education for positive impact on professionals working at all the various levels of the health care system. To reduce the occurrence of nosocomial infections, the need for continuous education and vigorous training must be considered. Therefore, the present research was done to investigate the level of knowledge, perception, and correlation on preventing HAI and also to find out the association of demographic variables with knowledge and perception on HAI among the health care workers.

MATeRIAlS AnD MeTHODS
The present study was a cross-sectional study conducted in Panimalar Medical College Hospital & Research Institute, Chennai, Tamilnadu, India. A semi-structured questionnaire framed by the researchers has been used to analyze the knowledge and perception of preventing nosocomial infections among health professionals in tertiary care centers. Those subjects who were willing to provide informed consent and also those who are working in the tertiary care hospitals were involved in the study. The questionnaire was given to the study participants for assessing knowledge and perception. The participants filled up the demographic details (1 to 11) of the questionnaire. Sequentially the next knowledge questionnaire from 12 to 34 ( yes or no questions) was filled. After that they have to complete the next perception questionnaire from 35 to 46, which was measured by using a 5 point Likert scale. In this study for analyzing the findings descriptive statistics have been used. The results of the study were estimated by using mean, standard deviation, and proportions.

Interpretation of the Scores
To assess the knowledge component, 23 questions were incorporated into the questionnaire assigning one (1) point for correct response and zero for the incorrect response. A cumulative score of ≤ 8 points was categorized as inadequate knowledge criteria; ≤ 15 points was considered as moderately adequate knowledge criteria and ≤ 23 points was considered as adequate knowledge. To assess the attitudes/perceptions 12 questions were incorporated into the survey instrument on a 5-point Likert scale. A score of ≤ 16points was considered as negative attitudes/perceptions, ≤ 32 points was considered as neutral attitudes/ perceptions, and a score of ≤ 48 points was considered as positive attitudes/perceptions.

Compliance with ethical standards
Approval

Demographic information of healthcare professionals
In the present study a total of 367 health care professionals participated, out of which the response rate obtained was 71.4% (262). In respect of gender majority of them were female 204 (78%), in profession majority of them from nursing 231 (88%), in educational qualification most of them were undergraduate 124 (47%), regarding professional experience most of them have more than 6-10 years of experience, regarding the specification of the working area most of them are working in high-risk area (ICU,NICU,ER,OT) table 1.
About the knowledge of the health care professionals majority of them (93%) has sufficient knowledge of HAI. 94% knew that respiratory tract infections are the major cause for HAI and also, they knew that in-patients are the most susceptible population to HAI. 91% agreed that health care workers are the main source of HAI. 87% of them knew that sick leave to be availed if they have infected with respiratory symptoms or gastrointestinal symptoms. 75% know that wearing gloves will prevent transmission of infection. 97% felt that the transmission of HAI can be reduced by washing hands with antiseptic. 67% of them accepted that the gloves must be changed while delivering health care to multiple patients. 42% (111 out of 262) felt that no need of washing hands before patient contact. 77% (202 out of 262) considered all patients as potentially contagious. 91% (239 out of 262) knew that masks to be provided to the patients with a cough during transfer out of room for other investigations. 81% (213 out of 262) experienced splash exposure of the patient's blood, vomit or other body fluids. 90% (235 out of 262) knew about the protocol for exposure to body fluid of seropositive cases. 91% (237 out of 262) were aware that daily used items like pen, mobile phone, apron, uniform acts as a carrier for hospital-acquired infections. 92 (241 out of 262) agreed that washing duty uniform or apron daily is mandatory. 81% (211 out of 262) stated yes for cleaning the stethoscope after examining each patient with an antiseptic (e.g.70 % alcohol). 68% were (179 out of 262) aware that there must be proper spacing (1.5 meters) between beds with a curtain between beds for infected patients in ward. 92% (241 out of 262) knew that OT culture and air sampling methods are done to monitor the presence or spreading of nosocomial infections within the hospital set up. 87 % (229 out of 262) were aware that the infectious agents can be transmitted to patients by visitors, which may have negative impact on the patient's outcome. 95% (248 out of 262) knew that frequent hand washing and avoidance of touching mouth and nose can effectively protect them from spreading the infectious microorganism during this outbreak seasons.
In relation to the perception of the health care professional's majority of them i.e 41% (107 out of 262) strongly agreed that HAI has a negative impact on the patient's outcome. 58% (153 out of 262) strongly agreed that HAI can be prevented through effective hand hygiene. 53% (140 out of 262) strongly agreed that improper hand hygiene and improper use of PPE is the reason for hospital- acquired infections. 71% strongly agreed that special precautions to be taken for HBV, HCV, HIV positive patients. 44% strongly agreed that patients living with HIV Antigen must be treated in an isolation ward. 78% strongly agreed that vaccination for health care workers is a must. 35% strongly disagreed that PPE is not needed when a health care worker is vaccinated. 51% strongly agreed that medical history and antibiotic usage history are important for treating multi-drug resistance microorganisms. 60% strongly agreed that used needles should not be recapped. 47% strongly agreed that performing hand hygiene is less likely to transmit infections to patients. The above table 4 portrays portrays the knowledge and perception of health care Knowledge and perception of health care professionals regarding the prevention of HAIs: Adequate knowledge was seen in 91% of the study participants. 95% of them had a high level of perception and 5% of them had a moderate level of perception.
This present study participant's level of knowledge on the prevention of HAI was 19.6 ± 2.7. The level of perception of the prevention of HAI was 52 ± 5.6 with a lowest being 33 and the highest being 60. Table 6 showed positive fair correlation between the level of knowledge and perception score on prevention of HAI with the r-value of 1 at P=0.006.
Below table 7 described the association of knowledge with the selected demographic variables, were significant at P=0.001.

DISCUSSIOn
Health-care associated infection (HAI) levels have reduced with the development of multifaceted infection prevention and control programs. 7 Updating the knowledge on current guidelines and protocols on preventing HAI will help the health care professionals to apply them in day to day practices. 8 In this study, 87% of the participants answered positively about infectious agents transmitted to patients by the visitors may have negative impacts on patient outcomes. 90% of the participants were aware that daily used items like pen, mobile phone, apron, and uniform will act as a carrier for Hospital-Acquired Infections. Similar level of awareness was revealed in other studies conducted by Khan et al and Haun et al. 9,10 The study results revealed that there was adequate knowledge (91%) on preventing HAIs among the participants of this study. Our findings were supported by various other studies which showed that more than 90% of health care professionals have exquisite knowledge on infection prevention [11][12][13] . Similarly, the research work of Allah-Bakhshian et al, had above average results about the knowledge of the professionals accessed in his study 14 . The results of the present study was not persistent with the results of the studies conducted to understand the level of knowledge on HAI, which revealed that more than 90% of the workers had inadequate knowledge about HAI [15][16][17] .
Many factors have an impact on the result of the study such as individual characteristics, education, and the number of practical training sessions attended. Researchers reported that the training of the healthcare professionals will have a positive impact on healthcare personnel by improving the knowledge and emphasized the need for regular mandatory educational training programs in every health care organization. 18 Implementation of continuous training programs and knowledge improvement have helped in reducing the incidence of patients progressing with HAI 19 .
A study conducted in Tamilnadu on using specific indicators for preventing HAI revealed that the infection control intervention should not only involve training and educating the health professionals but also it should address all the other factors like infrastructure, environmental, and personnel 20 . The major barriers of preventing HAI must be recognized by the administration. The infection control prevention programs must be supported through adequate personal, financial, and material supplies. Epidemiological surveillance of HAI is essential to understand the nature and extent of the problem, which also supports the health care workers in treating infections and helps in planning the prevention strategies to deliver a high quality-health care in any of the hospitals 20 .
In relation to perception (as per Table-3), the majority of them strongly agreed that HAI has a negative impact on the patient's outcome. 53% of the participants strongly agreed that improper hand hygiene and improper use of Personal Protective Equipment (PPE) is the reason for hospital-acquired infections. 71% of the participants strongly agreed that special precautions to be taken for HBV, HCV, HIV positive patients. 78% of the study subjects strongly agreed that vaccination for health care workers is a must. 51% of the participants strongly agreed that medical history and antibiotic usage history are important for treating multi-drug resistant microorganisms. 60% of the participants strongly agreed that used needles should not be recapped. The overall perception mean of this study was 52 ± 5.6, which was in line with the findings reported in the public health lieterature 21 .In our present investigation, the level of knowledge and perception on preventing hospital-acquired infections have a strong and positive fair correlation with the r-value of 1 at P=0.006. In support of our findings the positive correlation of working experience, the area of working versus the knowledge & perception of the HAIs was documented 18,22,23 .
In the present study, there exists an association between knowledge level versus selected demographic variables such as following protocol of hand hygiene, the training received on HAI within last year, and the presence of an infection control department in their institution at P=0.001. This result was similar to a study conducted in Chennai 15 . Out of the 262 study participants, 13% of health professionals have not undergone education on the prevention of HAIs which is in similarity with the observations of the study conducted by Jain et al. 24 91% of the study participants accepted that health care professionals are the major source for transmission of HAI. However, special priority should be given to interactive educational training that focus on infection control prevention in hospital settings. By conducting a continuous training program, it can be used as an inclusive model for enhancing the knowledge and also will help to resolve the misapprehension towards infectious diseases 25 .

CONClusiON
Overall, health care professionals in this study had adequate knowledge and perceptions with respect to the prevention of HAIs. Continuous education and vigorous training on HAIs will have a positive effect on improving the knowledge and perception at all levels of tertiary care health workers to prevent infections. In order to reduce the HAIs, policymakers, and the infection control team must take necessary combined efforts to implement and improve the required interventional strategies. In the future, researchers can consider stronger observational study designs to validate the knowledge, perception, practice, and attitude of the professionals working at the various levels of health care delivery systems, towards the prevention of HAIs.