Journal of Pure and Applied MicrobiologyVol. 2 No. 1

Antibacterial Activity of Various Crude Extracts of Justicia tranquebariensis

Arasan Elayaraja*, Sheikh Abdul Rahaman, Gananadhamu Samantalu and Devala Rao Garikapati

Department of Pharmaceutical Chemistry, KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada - 520 010 India.

Received on 30 November 2007 and accepted on 15 January 2008

 

ABSTRACT

The in vitro antibacterial activity of different extracts obtained from roots and rhizomes of Justicia tranquebariensis against different organisms namely Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Klebsiella pneumonia have been carried out. The prepared extracts from petroleum ether and hydro alcohol (50:50) were investigated with different concentrations. Our findings showed that both extracts have highest antibacterial activity in gram positive strains than gram negative strains. Also increase in concentration of each extract increases the antibacterial activity. Both the extracts showed significant broad spectrum anti-bacterial activity.

Keywords : Justicia tranquebariensis, Petroleum ether extract, Hydro alcoholic extract, MIC.