Journal of Pure and Applied MicrobiologyVol. 2 No. 1

Antibacterial Activity of Swertia chirata Buch.-Hams. A highly valuable medicinal herb

K. Balaraju1, S. Arokiyaraj1, P. Agastian 1, N. Thomas Paulraj1 and S. Ignacimuthu2

1Department of Plant Biology and Biotechnology, School of Life Sciences, Loyola College, Chennai-600 034, India. 2Entomology Research Institute, Loyola College, Chennai - 600 034, India.

Received on 20 February 2008 and accepted on 24 March 2008

 

ABSTRACT

In the present study we have carried out to evaluate the antibacterial activity of crude extracts from the whole plant of Swertia chirata Buch.-Hams. Hexane, ethyl acetate and methanol extracts were obtained by cold percolation method and their activity was carried out with gram positive and gram negative bacterial strains. Preliminary phytochemical screening was performed for all the extracts. In the present results ethyl acetate extract inhibited many bacteria with MIC values ranging from 0.312 to > 1 mg/ml. Phytochemical screening revealed the presence of terpenoids, steroids, flavonoids, alkaloids and carbohydrates. This study showed that S. chirata can be one of the potential sources of new antibacterial agents for the tested bacterial strains.

Keywords : Secondary metabolites, antibacterial activity.