Journal of Pure and Applied MicrobiologyVol. 6 No. 1

A Study on Toxic Effects and Luxative Activity of Senna (Cassia angustifolia Vahl.)

R. Sujatha, Jemima Beryl Mohankumar¹ and P. Shanmugasundaram²

Department of Nutrition and Dietetics, Government Arts and Science College for Women, Bargur, Krishnagiri District, Tamilnadu, India. ¹Department of Nutrition and Dietetics, P.S.G. College of Arts and Science College, Coimbatore, Tamilnadu, India. ²Department of Chemistry, Thiruvalluvar Government Arts College, Rasipuram, Namakkal District, Tamilnadu, India.

Received on 04 June 2011 and accepted on 12 July 2011



Senna is a medicinal plant variety grown predominantly in Tamilnadu and Gujarat. The pods and leaves of the plants are used in confectionary and herbal preparations. The two species used most often for medicinal purposes are Alexandrian senna and Tinnevelly senna. The Alexandrian variety is obtained mainly from Egypt and the Sudan. Tinnevelly senna is primarily cultivated in India. For the present study the senna plant was collected from Tirunnelveli district, Tamilnadu, India and the major active constituents sennoside A and B are identified, microbial analysis of senna leaf powder was carried out and the nutritive value of senna was determined. The toxic effect and laxative activity of senna leaf powder was carried out with animal model.

Keywords : Constipation, Cassia angustifolia, Senna, Sennosides, Toxicity, Laxative.