Journal of Pure and Applied MicrobiologyVol. 2 No. 1

Antimicrobial activity of Leaf extracts of Pterocarpus santalinus L. (Fabaceae)

K. Balaraju1, S. Arokiyaraj1, P. Agastian1*, K. Perinbam1 and S. Ignacimuthu2

1Department of Plant Biology and Biotechnology, School of Life Sciences, Loyola College, Chennai - 34, India. 2Entomology Research Institute, Loyola College, Chennai - 600 034, India.

Received on 30 December 2007 and accepted on 21 January 2008



The present study was carried out to evaluate the antimicrobial activity of leaf extract from P. santalinus. Hexane, ethyl acetate and methanol extracts were obtained by cold percolation method. Result indicated that P. santalinus exhibited significant antimicrobial activity at all the dosage tested (1.25 mg/disc, 2.5 mg/disc and 5 mg/disc). Ethyl acetate and methanol extracts were found to be active towards drug resistant strains. This study showed that leaf extract of P. santalinus can be a potential source of new antimicrobial agents for the tested drug resistant bacterial strains and fungi.

Keywords : multidrug resistant, medicinal plants, secondary metabolites.