Journal of Pure and Applied MicrobiologyVol. 4 No. 2

In vitro Antimicrobial activity and QSAR Studies of Some Quinazolinone Substituted Sulphones

Pramilla Sah* and Nirmala Kumari

Department of Chemistry, J.N.V. University, Jodhpur – 342 005, Rajasthan, India.

Received on 30 June 2010 and accepted on 06 August 2010

 

ABSTRACT

Seven new 2–(3–phenyl–6,8–disubstituted 4–oxo–(3H)–quinazolinyl)– 2’/4’/2’, 4’– substituted phenyl sulphones were screened against three bacterial strains E. coli, S. typhi and S. aureus and antifungal against A. flavus and Penicillium species. Some of them were found to be active.

Keywords : Sulphones, Antimicrobial activity.