Journal of Pure and Applied MicrobiologyVol. 4 No. 2

Mesoporphyrin (ix) Dihydrochloride as a Non-Selective Antimicrobial Agent

R.C. Jagessar¹* and S. Gomathinayagam²

¹Department of Chemistry, Faculty of Natural Sciences, University of Guyana, Turkeyen Campus, Guyana, South America, ²Faculty of Agriculture and Forestry University of Guyana, Berbice Campus, John’s, Guyana, South America.

Received on 08 January 2010 and accepted on 22 February 2010

 

ABSTRACT

Antimicrobial activity of mesoporphyrin ix dihydrochloride (1) was investigated using the Agar diffusion and Poison plate methods. Compound (1) was shown to be both antibacterial and antifungal with a higher degree of selectivity for S. aureus and C. albicans versus E. coli.

Keywords : Antimicrobial activity, Mesoporphyrin, Agar well diffusion, Poison plate methods.