Journal of Pure and Applied MicrobiologyVol. 9 No. 4

Antimicrobial Potential of Petroleum Ether Extract and Active Column Fractions of the Solanum incanum Leaves

S. Sundar1 and Y. Justin Koilpillai2

1Research Scholar,Faculty of Bio-Engineering, Sathyabama University, Chennai- 600 119, India. 2Department of Botany, St. Joseph?s College, Trichirappalli, Tamilnadu, India.

Received on 16 June 2015 and accepted on 10 August 2015

 

ABSTRACT

Solanum incanum belongs to Solanaceae family and are extensively used in the treatment of stomachache, colic, headache, pneumonia, rheumatism and other pathological conditions. The therapeutic activity of the solanum incanum has been attributed to their content present in it. Phytoconstituents analysis showed the presence of Saponins, Tannins, Alkaloids and Flavonoids. Anti microbial activity of extracts from solanum incanum leaf has been evaluated against both gram positive and gram negative microorganisms such as E.coli, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Bacillus subtilis, and Bacillus aureus. Petroleum ether extract showed excellent antibacterial activity against E. coli (18 mm), P. aeruginosa (16 mm) and B. Subtilis (15 mm) and the MIC and MBC of Bacillus subtilis was found to be 7.81 ?g/ml and 3.91 ?g/ml respectively.

Keywords : Antimicrobial activity, Solanum incanum, Phytoconstituents, Solvent extracts.