Journal of Pure and Applied MicrobiologyVol. 9 No. 4

The Seroprevalence of Brucellosis Among Blood Donors in Hamadan Province, West of Iran

Zahra Naseri1, Farideh Kamarehei2 , Seyyed Hamid Hashemi2, Abbas Moghimbeigi2, Mona Eslami2, Fatemeh Torkaman Asadi2, Saied Khakizadeh2, Afshin Mohammadi1 and Mohammad Yousef Alikhani2*

1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion, Hamadan, IR Iran. 2Brucellosis research center, Hamadan University of Medical Sciences, Hamedan, IR, Iran.

Received on 29 September 2015 and accepted on 09 November 2015

 

ABSTRACT

Brucellosis is a widespread zoonotic disease. Person to person transmission is rare, whereas, blood transfusion and tissue transplantation are known sources of brucellosis especially in endemic areas. This study aimed to determine the prevalence of brucellosis in blood donors in Hamadan province, west of Iran. Blood specimens were collected from 600 blood donors who referred to Hamadan Blood Organization between January and June 2014. Antibody titer e? 1:80 in wright and coombs wright and e? 1:20 in 2ME tests were considered positive. Anti-brucella IgG checked with Enzyme-Linked Immunosorbent Assay (ELISA) that titer >12 U/mL were considered positive. Among 600 specimens, 30% were inhabitants of rural areas. 62.7% had history of consumption of unpasteurized dairy products and 10.5% had history of contact with animals. In our blood donor population, 2 cases (0.3%) with wright and coombs wright test, 3 cases (0.5%) with the 2ME test and 76 cases of 544 (14%) with ELISA were found positive for Brucella antibodies that 13% of them showed signs and symptoms of brucellosis before the last two years. Based on our findings and due to interrupt transmission of blood-borne infections, we suggest questioning from all blood donors about symptoms of brucellosis before blood donation.

Keywords : Seroprevalence, Brucellosis, Blood donors, Iran.