Journal of Pure and Applied MicrobiologyVol. 9 No. Special Edition Nov. 2015

Nano Silver Particles in Biomedical and Clinical Applications : Review

Krishna Suresh Babu Naidu1*, Patrick Govender2 and Jamila K. Adam1

1Department of Biomedical and Clinical Technology, Durban University of Technology, Durban 4000, South Africa. 2Department of Biochemistry, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.

Received on 20 July 2015 and accepted on 09 September 2015

 

ABSTRACT

Nanotechnology is most promising arena for generating new applications in medicine and advancing rapidly due to the great progress achieved in various fileds including electronics, machanics, cosmetics, food, etc. In order to successfully bifunctionalise nanoparticles for a given biomedical application, a wide range of chemical, physical and biological factors are to be taken into account. Silver nanoparticles (AgNPs) at nanoscale exhibits strong antibacterial activity vowing to their large surface to volume ratios and crystallographic surface structure. Nanosilver particles have been widely used in a range of biomedical applications including diagnosis, treatment, medical device coating, drug delivery and personal health care products. With the growing application of nanosilver particles in medical contexts, it is becoming necessary for a better understanding the mechanisms of action, biological interactions and their potential toxicity on exposure. This review aims to provide critical assessment of the current understanding of antibacterial activity, biomedical and clinical applications of silver nanoparticles.

Keywords : Antibacterial, , Biomedical, Clinical, Nanosilver, Applications.