Journal of Pure and Applied MicrobiologyVol. 9 No. Special Edition May. 2015

Human Bocavirus in Hospitalized Iranian Adults with Respiratory Tract Infections during January-June 2014

Helya Sadat Mortazavi1, Seyed Hamidreza Monavari2*, Hamidreza Molaee3, Hossein Keyvani4 and Angila Ataee Pirkooh5

1Molecular laboratory ,Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. 2-5Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Received on 19 October 2014 and accepted on 02 January 2015

 

ABSTRACT

The epidemiology of respiratory human bocavirus (HBoV) infection has not been described in Tehranís adult and to determine the epidemiological and clinical characteristics associated with HBoV infection, a population of adults hospitalized with respiratory tract infections were chosen. Throat swab samples were collected from 91 hospitalized adults aged between 29 to 91 year and Real-time PCR TaqMan was used to screen specimens by amplifying a part of the NP1 gene. HBoV was detected in 6 adults (6.6%). Mean age was 76 years and 67% of patients were female. The most common symptoms were wheezing (100%), tachypnea (100%), cough (100%), rhinorrhea/pharyngitis (83.33%) and fever (83.33%) which clinically diagnosed by a physician. Gastrointestinal symptoms was present only in 1 patient (16.6%). In our study the distribution of HBoV was influenced by temperature, relative humidity and precipitation. HBoV is circulating in Tehran and is associated with both upper and lower respiratory tract disease in adults.

Keywords : Respiratory Infections, Adults, Human Bocavirus, Real-time PCR.