Journal of Pure and Applied MicrobiologyVol. 8 No. 6

Screening of Selected Single Plants and its Siddha Formulation for Antibacterial and Antifungal Activity

M.S. Shree Devi1*, V. Ravichandiran2 and S. Jeyakumari3

1Reader, Sivaraj Siddha Medical College, Salem, Tamilnadu, India. 2Director, School of Pharmaceutical Sciences, Vels University, Chennai, India. 3Prof. Department of Pharmacognosy, Vels University, Chennai, India.

Received on 11 July 2014 and accepted on 23 October 2014



The study deals with antibacterial and antifungal activity of selected single plants (Adathoda vasica, Ocimum tenuiflorum, Solanum xanthcarpum, Tylophora asthmatica) and its Siddha formulation. The antibacterial and antifungal activity was determined using the hole-in-plate bio assay procedure. Staphylococcus aureus, Escherichia Coli, Pseudomonous arrigonosa, Bacillus subtilis (antibacterial) Candida albicans and Aspergillus niger (antifungal) were used as the test microorganisms. In this microbial study the findings shows Siddha formulation are having more antibacterial activity than antifungal activity which is determined by zone of inhibition, MIC and MBC on different bacterial and fungal strains. Further, the results of antibacterial activity of siddha formulation were compared with standard drug Amoxcillin and for anti fungal activity of siddha formulation were compared with standard drug chloramphenicol.

Keywords : Siddha formulation, Antimicrobial activity, Antifungal activity, Hole-in-plate bio assay.