Journal of Pure and Applied MicrobiologyVol. 8 No. May 2014 Special Edition

Potential Antimicrobial, Antioxidant and Anityrosenase Activities achieved by Selected Species of Marine Macroalgae

Amal H. Hamza1,3, Widad Al-Bishri1, H.H. Omar2,4 and Enas N. Danial1,5*

1Department of Biochemistry, Faculty of Science for Girls, King Abdulaziz university, Jeddah, Saudi Arabia. 2Biological Science Department, Faculty of Science for Girls, King Abdulaziz University, Jeddah, Saudi Arabia. 3Biochemistry and Nutrition Department, Faculty of Women, Ain Shams University, Cairo Egypt. 4Botany Department, Faculty of Science, Tanta University, Egypt. 5Chemistry of Natural and Microbial Products Department, National Research Center, Dokki, Cairo, Egypt.

Received on 20 February 2014 and accepted on 01 May 2014

 

ABSTRACT

Marine macroalgae are very rich source of phenolic compounds endowed with antioxidant and antimicrobial properties. The aim of this study was to evaluate the bioactivity composition of three selected green, brown and red algae ? viz., Halimeda opuntia, Padina pavonica and Halymenia sp., respectively from Jeddah coast in Saudi Arabia. The antimicrobial properties against pathogenic Grame positive, Grame negative bacteria and fungi were tested. In vitro antioxidant activities including 1, 1-Diphenyl -2-picrylhydrazyl (DPPH) radical scavenging, antityrosenase activity and lipid peroxidation activity were studied. The highest amount of phenolic compound was found in the extract obtained from Padina pavonica this extract also showed good antioxidant activity expressed by its capacity to scavenge superoxide anion and to inhibit lipid peroxidation. Halimeda opuntia, Padina pavonica exhibited good antioxidant activity when compared to Halymenia sp. The maximum antimicrobial activity was shown by the extract of Halimeda opuntia, Padina pavonica against Klebsiella pneumoniae ATCC 27736 (32mm). The results showed that marine macroalgae exhibited varying degrees of antioxidant and antimicrobial properties.

Keywords : Marine macroalgae, antimicrobial, antityrosenase, antioxidant, total phenolic.