Journal of Pure and Applied MicrobiologyVol. 8 No. May 2014 Special Edition

Application of Macroporous Resin to Recover and Purify Sucralose-6-ester from the Crystalline Residue

Bin Shen1*, Bo Tang1, Jinshan Wu2 and Guoting Zhu2

1School of Chemistry and Chemical Engineering, Southeast University, Rd. 2, Southeast University, Jiangning District, Nanjing - 211189, China. 2JK Sucralose Inc, Jiangsu Sheyang Economic Development Zone, Sheyang - 224300, China.

Received on 12 April 2014 and accepted on 09 May 2014

 

ABSTRACT

A method for recovering and purifying the sucralose-6-ester from the crystallization residue was investigated by using macroporous resin. The residue containing the target compound was dissolved in water to prepare sample solution. Static adsorption/desorption characteristics of three macroporous resins for separating sucralose-6-ester from crude extracts have been studied, and D101 resin was chosen for further experiment. The dynamic adsorption/desorption experiments were carried out to optimize the separation process. Under these optimization conditions, the purity of sucralose-6-ester was increased from 21.3% to 64.7% in two separations. After separated twice, it reached the purity of sucralose-6-ester in the mixture of chlorination reaction, and it can be added to the conventional process for further separation and purification. This study provides a novel, effective, environmental and economical method for recovery and purification of sucralose-6-ester.

Keywords : Sucralose-6-ester, Macroporous resin, Separation, Recovery.