Journal of Pure and Applied MicrobiologyVol. 6 No. Special Edition Oct. 2012

Trends in Seroprevalence of Hepatitis C and Syphilis in North Indian Tertiary Health Care Center- A Five Year Retrospective Study

Suhailur Rehman, Sayeedul Hasan Arif, Ghazala Mehdi, Kafil Akhtar, Shamsuzzaman and Murad Ahmed

Departmentof Pathology, J.N. Medical College, Aligarh Muslim University, Aligarh, India.

Received on 04 March 2012 and accepted on 10 June 2012



Transfusion transmissible infections like human immunodeficiency virus (HIV), Hepatitis B, Hepatitis C and syphilis are the greatest threats for the recipients blood products. This study aimed to determine the seroprevalence trends of hepatitis C and syphilis in the last five years.A retrospective analysis of blood donors from January 2007 to September 2011 was conducted in blood bank in JN Medical College, AMU Aligarh. Blood samples were screened for anti HCV by enzyme linked immunosorbent assay (ELISA) and syphilis by rapid plasma reagin (RPR).A total of 53950 healthy blood donors were tested, out of which 51266 (95.02%) were males and 2684 (4.98%) were females. The overall Seroprevalence of HCV and syphilis was 169 (0.31%) and 164 (0.30%) respectively. There were 21(0.19%) cases of HCV in 2007, 27 (0.26%) in 2008, 35(0.36%) in 2009, 38(0.32%) in 2010 and 48 (0.42%) in 2011 showing increased prevalence from 2007 to 2011. No such increasing trend was seen in case of syphilis;however there was sudden increase in seroprevalence of syphilis in 2011 due to change in the testing kit which was more sensitive.

Keywords : Hepatitis C, Syphilis, Seroprevalence.