Journal of Pure and Applied MicrobiologyVol. 7 No. 4

Epidemiology and Risk Factors of Hepatitis Delta Infection in Turkey

Celal Ayaz1, Suda Tekin Koruk2, Aysun Yalci3, Tansu Yamazhan4, Bilgehan Aygen5, Selma Tosun6, Tuba Dal7, Mustafa Kemal Celen1 and Fehmi Tabak8

1Department of Infectious Diseases, Faculty of Medicine, Dicle University, Diyarbakir, Turkey. 2Department of Infectious Diseases, Faculty of Medicine, Harran University Sanliurfa, Turkey. 3Department of Infectious Diseases, Faculty of Medicine, Ankara University, Ankara, Turkey. 4Department of Infectious Diseases, Faculty of Medicine, Ege University, Izmir, Turkey. 5Department of Infectious Diseases, Faculty of Medicine, Erciyes University, Kayseri, Turkey. 6Department of Infectious Diseases, Manisa State Hospital, Manisa, Turkey. 7Department of Microbiology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey. 8Department of Infectious Diseases, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Received on 28 February 2013 and accepted on 01 April 2013

 

ABSTRACT

This study is aimed to investigate the prevalence and risk factors of HDV co-infection in patients with chronic HBV infection in Turkey, where HBV infection is endemic. The date of this study was obtained from Turk-Hep-Net project. The project includes real-life cohort of HBV patients from 15 centers in Turkey and is supported by Viral Hepatitis Society. Of the 7366 HBsAg positive individuals tested for the presence of anti-HDV antibodies, 63,6 were male and 36.4 % were female. Of the 7366 HBsAg positif patients, 206 (2.8%) contained anti-HDV. Southeastern Anatolia Region of the country's anti-HDV positivity rate was found to be 4.5%. The risk factors in anti-HDV positivity patient were; male gender, long-term (>5 year) HBsAg positivity and living in Southeastern Anatolia. Our study revealed that recognizing the risk factors associated with HBV and HDV co-infection will be beneficial to control of these infections.

Keywords : HDV, HBsAg, Risk factors, Turkey.