Journal of Pure and Applied MicrobiologyVol. 2 No. 2

Antimicrobial study of luteolin 7-O-a-L-rhamnopyranoside from heartwood of Terminalia bellerica (Roxb.)

Rishi Kant Asati1*, Madhuri Singhal1 and Mohini Saxena2

1Department of Chemistry, Govt. M.L.B. Post Graduate College, Bhopal - 462 003, India. 2Advanced Materials and Processes Research Institute (CSIR), Bhopal - 462 026, India.

Received on 22 April 2008 and accepted on 16 July 2008

 

ABSTRACT

Terminalia bellerica (Roxb.) is an important indigenous deciduous medicinal plant and its fruit is an important ingredient of herbal formulation ‘Triphala’. In our study, we isolated compound luteolin 7-O-a-L-rhamnopyranoside from the chloroform: ethyl acetate [in the ratio of 70:30] fraction of 95% ethanolic extract of Terminalia bellerica heartwood. Further studies indicated that luteolin 7-O-a-L-rhamnopyranoside has an anti-bacterial effect against Escherichia coli, Salmonella Stanley, Bacillus anthracis and Klebsiella pneumonia. In addition to that luteolin 7-O-a-L-rhamnopyranoside has an anti-fungal activity against Aspergillus niger, Aspergillus flavus, Chrysoporium tropicum. The results in the present study clearly indicate that the isolated compound possess potential broad spectrum antimicrobial activity.

Keywords : Terminalia bellerica, antimicrobial, luteolin 7-O-a-L-rhamnopyranoside.